Radiotherapy alters expression of molecular targets in prostate cancer in a fractionation- and time-dependent manner

Abstract The Battery Trays efficacy of molecular targeted therapy depends on expression and enzymatic activity of the target molecules.As radiotherapy modulates gene expression and protein phosphorylation dependent on dose and fractionation, we analyzed the long-term effects of irradiation on the post-radiation efficacy of molecular targeted drugs.

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Producing non-steady-state gaits (starting, stopping, and turning) in a biologically realistic quadrupedal simulation

Multibody dynamic analysis (MDA) has become part of the standard toolkit used to reconstruct the biomechanics of extinct animals.However, its use is currently almost exclusively limited to steady state activities such as walking and running at constant velocity.If we want to reconstruct the full range of activities that a given morphology can achie

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